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  1. Home/
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  4. San Francisco 49ers vs Miami Dolphins

San Francisco 49ers vs Miami DolphinsNFL Picks, Prediction & Odds • Sep 20 • 04:25 PM

NFL

Sunday, September 20, 2026

San Francisco 49ers logo

San Francisco 49ers

0-0
Sep 20 • 04:25 PM
Starting Now
Miami Dolphins logo

Miami Dolphins

1Picks

Experts Betting This Game

1 expert has a pick on San Francisco 49ers vs Miami Dolphins

View Expert Picks
Sean Kuchman

Sean Kuchman

70% Win Rate
Pick on this game
Premium pick +100Unlock
Sean Kuchman

Sean Kuchman

70% Win Rate
Pick on this game
Premium pick +100Unlock

Our Prediction

San Francisco 49ers logoSan Francisco 49ers15%
85%Miami DolphinsMiami Dolphins logo
San Francisco 49ers logo
San Francisco 49ers
VS
Miami Dolphins logo
Miami Dolphins
Confidence
Medium

We predict Miami Dolphins

Key Factors

Betting Odds

Betting odds imply a 93% chance for Miami Dolphins

1

Expert Picks Available

Professional handicappers have analyzed this game

Betting Odds

San Francisco 49ers logoSan Francisco 49ers
Miami DolphinsMiami Dolphins logo
Spread
-13.50
-105
13.50
-115
Moneyline
-1000
FAV
+660
Total (O/U 45.50)
Over
-102
Under
-120

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Frequently asked questions

Who is favored to win San Francisco 49ers vs Miami Dolphins?▾

San Francisco 49ers are favored over Miami Dolphins based on the latest moneyline (San Francisco 49ers -1,000, Miami Dolphins +660).

What is the point spread for San Francisco 49ers vs Miami Dolphins?▾

San Francisco 49ers -13.50, Miami Dolphins 13.50. Spread reflects the projected margin between the two teams.

What is the over/under for San Francisco 49ers vs Miami Dolphins?▾

The total (over/under) is 45.50. Over 45.50 or under 45.50 wins respectively.

When is San Francisco 49ers vs Miami Dolphins?▾

San Francisco 49ers vs Miami Dolphins is scheduled for Sep 20 at 04:25 PM ET.

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See all NFL picks →
1

Expert Picks Available

Professional handicappers have analyzed this game

Betting Odds

San Francisco 49ers logoSan Francisco 49ers
Miami DolphinsMiami Dolphins logo
Spread
-13.50
-105
13.50
-115
Moneyline
-1000
FAV
+660
Total (O/U 45.50)
Over
-102
Under
-120
PicksToday logo

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Please gamble responsibly. If you have a gambling problem, please visit ncpgambling.org