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  1. Home/
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  4. Buffalo Bills vs New England Patriots

Buffalo Bills vs New England PatriotsNFL Picks, Prediction & Odds • Oct 4 • 01:00 PM

NFL| Final

Sunday, October 4, 2026

Buffalo Bills logo

Buffalo Bills

26-29
Final
New England Patriots logo

New England Patriots

9Picks

Experts Betting This Game

9 experts have a pick on Buffalo Bills vs New England Patriots

View Expert Picks
SWJ Sports

SWJ Sports

30% Win Rate
Pick on this game
Premium pick +100Unlock
Keylor Santos

Keylor Santos

70% Win Rate
Pick on this game
Premium pick +100Unlock
Alex Smart

Alex Smart

70% Win Rate
Pick on this game
Premium pick +100Unlock
Scott's Picks

Scott's Picks

70% Win Rate
Pick on this game
Premium pick +100Unlock
Sniper Wes

Sniper Wes

70% Win Rate
Pick on this game
Premium pick +100Unlock
SWJ Sports

SWJ Sports

30% Win Rate
Pick on this game
Premium pick +100Unlock
Keylor Santos

Keylor Santos

70% Win Rate
Pick on this game
Premium pick +100Unlock
Alex Smart

Alex Smart

70% Win Rate
Pick on this game
Premium pick +100Unlock
Scott's Picks

Scott's Picks

70% Win Rate
Pick on this game
Premium pick +100Unlock
Sniper Wes

Sniper Wes

70% Win Rate
Pick on this game
Premium pick +100Unlock

Pre-Game Prediction

Buffalo Bills logoBuffalo Bills74%
26%New England PatriotsNew England Patriots logo
Buffalo Bills logo
Buffalo Bills
VS
New England Patriots logo
New England Patriots
Confidence
Medium

We predict Buffalo Bills

Key Factors

Betting Odds

Betting odds imply a 74% chance for Buffalo Bills

Prediction Result

✗ Incorrect
Buffalo Bills
26
-
New England Patriots
29
Our Pick
Buffalo Bills
Actual Winner
New England Patriots
9

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Frequently asked questions

Who is favored to win Buffalo Bills vs New England Patriots?▾

Buffalo Bills are favored over New England Patriots based on the latest moneyline (Buffalo Bills -345, New England Patriots +275).

What is the point spread for Buffalo Bills vs New England Patriots?▾

Buffalo Bills -7.00, New England Patriots 7.00. Spread reflects the projected margin between the two teams.

What is the over/under for Buffalo Bills vs New England Patriots?▾

The total (over/under) is 49.00. Over 49.00 or under 49.00 wins respectively.

When is Buffalo Bills vs New England Patriots?▾

Buffalo Bills vs New England Patriots is scheduled for Oct 4 at 01:00 PM ET.

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    Sun, Oct 25
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    Sun, Oct 25
See all NFL picks →
9

Expert Picks Available

Professional handicappers have analyzed this game

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