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  1. Home/
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  3. NBA/
  4. Philadelphia 76ers vs Cleveland Cavaliers

Philadelphia 76ers vs Cleveland CavaliersNBA Picks, Prediction & Odds • Oct 22 • 07:10 PM

NBA

Thursday, October 22, 2026

Philadelphia 76ers logo

Philadelphia 76ers

0-0
Oct 22 • 07:10 PM
Starting Now
Cleveland Cavaliers logo

Cleveland Cavaliers

18Picks

Experts Betting This Game

18 experts have a pick on Philadelphia 76ers vs Cleveland Cavaliers

View Expert Picks
Sports Hub - FREE PICKS

Sports Hub - FREE PICKS

70% Win Rate
Pick on this game
Premium pick +100Unlock
Knup Sports - POTD

Knup Sports - POTD

70% Win Rate
Pick on this game
Premium pick +100Unlock
GA Algorithm

GA Algorithm

30% Win Rate
Pick on this game
Premium pick +100Unlock
Frankie the Fan

Frankie the Fan

70% Win Rate
Pick on this game
Premium pick +100Unlock
Skyler Lockheart

Skyler Lockheart

38% Win Rate
Pick on this game
Premium pick +100Unlock
Sports Hub - FREE PICKS

Sports Hub - FREE PICKS

70% Win Rate
Pick on this game
Premium pick +100Unlock
Knup Sports - POTD

Knup Sports - POTD

70% Win Rate
Pick on this game
Premium pick +100Unlock
GA Algorithm

GA Algorithm

30% Win Rate
Pick on this game
Premium pick +100Unlock
Frankie the Fan

Frankie the Fan

70% Win Rate
Pick on this game
Premium pick +100Unlock
Skyler Lockheart

Skyler Lockheart

38% Win Rate
Pick on this game
Premium pick +100Unlock

Our Prediction

Philadelphia 76ers logoPhiladelphia 76ers56%
44%Cleveland CavaliersCleveland Cavaliers logo
Philadelphia 76ers logo
Philadelphia 76ers
VS
Cleveland Cavaliers logo
Cleveland Cavaliers
Confidence
Low

We predict Philadelphia 76ers

Key Factors

Betting Odds

Betting odds imply a 56% chance for Philadelphia 76ers

18

Expert Picks Available

Professional handicappers have analyzed this game

Betting Odds

Philadelphia 76ers logoPhiladelphia 76ers
Cleveland CavaliersCleveland Cavaliers logo
Spread
-2.50
-106
2.50
-106
Moneyline
-139
FAV
+122
Total (O/U 236.50)
Over
-108
Under
-108

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Frequently asked questions

Who is favored to win Philadelphia 76ers vs Cleveland Cavaliers?▾

Philadelphia 76ers are favored over Cleveland Cavaliers based on the latest moneyline (Philadelphia 76ers -139, Cleveland Cavaliers +122).

What is the point spread for Philadelphia 76ers vs Cleveland Cavaliers?▾

Philadelphia 76ers -2.50, Cleveland Cavaliers 2.50. Spread reflects the projected margin between the two teams.

What is the over/under for Philadelphia 76ers vs Cleveland Cavaliers?▾

The total (over/under) is 236.50. Over 236.50 or under 236.50 wins respectively.

When is Philadelphia 76ers vs Cleveland Cavaliers?▾

Philadelphia 76ers vs Cleveland Cavaliers is scheduled for Oct 22 at 07:10 PM ET.

More NBA picks

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    Thu, Oct 22
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    Fri, Oct 23
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    Fri, Oct 23
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    Fri, Oct 23
  • Golden State Warriors vs Memphis Grizzlies
    Fri, Oct 23
See all NBA picks →
18

Expert Picks Available

Professional handicappers have analyzed this game

Betting Odds

Philadelphia 76ers logoPhiladelphia 76ers
Cleveland CavaliersCleveland Cavaliers logo
Spread
-2.50
-106
2.50
-106
Moneyline
-139
FAV
+122
Total (O/U 236.50)
Over
-108
Under
-108
PicksToday logo

Expert sports betting picks and predictions

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21+Bet responsibly. Picks are for entertainment — gambling involves risk.

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Please gamble responsibly. If you have a gambling problem, please visit ncpgambling.org