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  1. Home/
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  3. MLB/
  4. St. Louis Cardinals vs Chicago White Sox

St. Louis Cardinals vs Chicago White SoxMLB Picks, Prediction & Odds • Sep 12 • 07:16 PM

MLB| Final

Saturday, September 12, 2026

St. Louis Cardinals logo

St. Louis Cardinals

5-6
Final
Chicago White Sox logo

Chicago White Sox

9Picks

Experts Betting This Game

9 experts have a pick on St. Louis Cardinals vs Chicago White Sox

View Expert Picks
Knup Sports - POTD

Knup Sports - POTD

70% Win Rate
Pick on this game
Premium pick +100Unlock
Pro Picks - James

Pro Picks - James

70% Win Rate
Pick on this game
Premium pick +100Unlock
Luke Reynolds

Luke Reynolds

70% Win Rate
Pick on this game
Premium pick +100Unlock
Trevor Collins

Trevor Collins

30% Win Rate
Pick on this game
Premium pick +100Unlock
Gino De Luca

Gino De Luca

70% Win Rate
Pick on this game
Premium pick +100Unlock
Knup Sports - POTD

Knup Sports - POTD

70% Win Rate
Pick on this game
Premium pick +100Unlock
Pro Picks - James

Pro Picks - James

70% Win Rate
Pick on this game
Premium pick +100Unlock
Luke Reynolds

Luke Reynolds

70% Win Rate
Pick on this game
Premium pick +100Unlock
Trevor Collins

Trevor Collins

30% Win Rate
Pick on this game
Premium pick +100Unlock
Gino De Luca

Gino De Luca

70% Win Rate
Pick on this game
Premium pick +100Unlock

Pre-Game Prediction

St. Louis Cardinals logoSt. Louis Cardinals50%
50%Chicago White SoxChicago White Sox logo
St. Louis Cardinals logo
St. Louis Cardinals
VS
Chicago White Sox logo
Chicago White Sox
Confidence
Low

We predict Chicago White Sox

Key Factors

Betting Odds

Betting odds imply a 50% chance for Chicago White Sox

Prediction Result

✓ Correct
St. Louis Cardinals
5
-
Chicago White Sox
6
Our Pick
Chicago White Sox
Actual Winner
Chicago White Sox
9

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Frequently asked questions

Who is favored to win St. Louis Cardinals vs Chicago White Sox?▾

Chicago White Sox are favored over St. Louis Cardinals based on the latest moneyline (St. Louis Cardinals -108, Chicago White Sox -111).

What is the point spread for St. Louis Cardinals vs Chicago White Sox?▾

St. Louis Cardinals 1.50, Chicago White Sox -1.50. Spread reflects the projected margin between the two teams.

What is the over/under for St. Louis Cardinals vs Chicago White Sox?▾

The total (over/under) is 8.50. Over 8.50 or under 8.50 wins respectively.

When is St. Louis Cardinals vs Chicago White Sox?▾

St. Louis Cardinals vs Chicago White Sox is scheduled for Sep 12 at 07:16 PM ET.

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9

Expert Picks Available

Professional handicappers have analyzed this game

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